SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health.&ampnbsp; Numerous studies have indicated that SAMe can help to temporarily alleviate aches and pains resulting from overexertion or stress. &ampnbsp;Therefore, SAMe is a natural product that can be part of a nutritional program for pain management. &ampnbsp;In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the regulation of mood.&ampnbsp; NOW&ampreg; SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.*