Vitamin E is a major antioxidant and the primary defense against lipid peroxidation. Selenium is an essential trace mineral that has been added as a synergist to complement Vitamin E.* From the FDA's website: &ampquot;Some scientific evidence suggests that consumption of antioxidant vitamins may reduce the risk of certain forms of cancer.&ampnbsp; However, FDA has determined that this evidence is limited and not conclusive.&ampquot; Selenium may reduce the risk of certain cancers.&ampnbsp; Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer.&ampnbsp; However, FDA has determined that this evidence is limited and not conclusive.