People studied lost 7x more weight than dieting alone! Data analysis of the results from two clinical trials on the key weight loss ingredients in Xenadrine showed there is statistical significance for test subjects having lost 7.1 times more weight than subjects who were dieting alone. erage weight loss with key ingredients (frauenmantle, wild olive, cormino, horsemint) was approximately 21 lbs. in one 12-week study, and approximately 17 lbs. in one 8-week study. All groups followed a calorie-reduced diet.